Contribution information

Title Preconcentration of electrically charged molecules in microfluidic systems with ion-exchange membranes
Status Accepted
Final type Lecture
Final session Separation processes
Authors P., Kovář1, Z., Slouka2, D., Tichý3
1 UCT Prague, Prague, Czechia
2 UCT Prague, Department of chemical engineering, Prague, Czechia
3 UCT Prague, Department of chemical engineering, Prague, Czechia
Uploaded abstract link
Brief content The lecture presents an original microfluidic separator using the combination of electrokinetic and hydrodynamic forces for preconcentration of electrically charged molecules. The design of the microfluidic separator and its principle of operation are presented. The key component is ion-exchange membranes which generate non-linear gradient of electric field in the device. Molecules of fluorescein are used to study the effects of the geometry of the channel and external conditions such as applied electric field, flow rate and time. Fluorescently labeled nucleic acids are employed as model biomolecules to verify its preconcentration function intended for microfluidic point-of-care devices.
ID 39